پوشش واکسیناسیون هپاتیت B در کارکنان درمانی ایران: یک مطالعه مرور سیستماتیک و متاآنالیز

Background and Objectives: In this regard, in addition to reducing exposure, the most effective way to prevent hepatitis B is vaccination. The coverage of hepatitis B vaccination in the Iranian Health Personnel is reportedly different in various studies and there is not an overall estimate of it. Therefore, the present study was conducted to determine the immune response to hepatitis B vaccine among Iranian Health Personnel using the meta-analysis method. Methods: This study was a systematic review of the Iranian databases, including Magiran, Iran Medex, IRANDOC, SID, MEDLIB and international databases, including Scopus, PubMed, ScienceDirect and the Google Scholar search engine without any time limit to 2015 using standard Persian and English keywords. Searches were conducted by two researchers independently. Meta-analysis was performed using STATA, version 11.1 to combine data through Random Effects Model. Results: We evaluated 6311 subjects in 21 studies. The history of injection and complete coverage of hepatitis B vaccination in the Health Personnel was 86.9% (CI: 95%, 83-90.7) and 70.3% (CI: 95%, 65.6-75), respectively. The minimum and maximum vaccination coverage were related to the North (52.7%) and West of Iran (87.2%), respectively. Conclusion: The coverage of hepatitis B vaccination in Iranian Health Personnel is less than European countries, which requires new management strategies and policies to maximize hepatitis B vaccination in high risk professional groups.